Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 7/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.51 |
| ▸ | HTR1A | P08908 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760327 | 0.93 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6767401 | 0.86 | ADRA1D (0.37) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6760336 | 0.81 | ADRA1D (0.76) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6760326 | 0.75 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7470285 | 0.71 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BHTR1AADRA2A | |
| SCHEMBL9028670 | 0.70 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL9028312 | 0.70 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL9028303 | 0.70 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6763076 | 0.70 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9027516 | 0.69 | ADRA1D (0.68) | ADRA1DADRA1AADRA1BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039023-A1 | Therapeutic agents | KNOLL GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039023-A1 | Therapeutic agents | AMY1A, PARK7, SNCA | ADRA1D 16/4885ADRA1A 27/4885ADRA1B 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.