Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 8/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760337 | 0.86 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6760327 | 0.81 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6760338 | 0.81 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6760339 | 0.81 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7684365 | 0.76 | ADRA1D (0.36) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL7684360 | 0.76 | ADRA1D (0.36) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL6760336 | 0.69 | ADRA1D (0.76) | ADRA1DADRA1AADRA1BHTR1ADRD2 | |
| SCHEMBL909508 | 0.69 | HTT (0.46) | DRD2DRD4DRD3LMNAMEN1 | |
| SCHEMBL909936 | 0.69 | HTT (0.46) | DRD2DRD4DRD3LMNAMEN1 | |
| SCHEMBL909506 | 0.69 | HTT (0.46) | DRD2DRD4DRD3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039023-A1 | Therapeutic agents | KNOLL GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039023-A1 | Therapeutic agents | AMY1A, PARK7, SNCA | ADRA1D 16/4885ADRA1A 27/4885ADRA1B 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.