Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761071 | 1.00 | LMNA (0.48) | LMNAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL7381723 | 0.83 | ALDH1A1 (0.55) | LMNAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL7465058 | 0.83 | PDE4A (0.48) | — | |
| SCHEMBL7465061 | 0.83 | PDE4A (0.48) | — | |
| Hydrochloric Acid SCHEMBL7459498 | 0.82 | PDE4A (0.47) | — | |
| Hydrochloric Acid SCHEMBL7378460 | 0.82 | PDE4A (0.47) | — | |
| SCHEMBL7438218 | 0.80 | MAPT (0.55) | LMNAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL7438208 | 0.80 | MAPT (0.55) | LMNAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL7438224 | 0.80 | MAPT (0.55) | LMNAPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL7431914 | 0.80 | MAPT (0.51) | LMNAPOLBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180938-A1 | Novel butadiene derivatives, process for preparation of the same and intermediates for the synthesis thereof | TANABE SEIYAKU CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180938-A1 | Novel butadiene derivatives, process for preparation of the same and intermediates for the synthesis thereof | SERPINE1, SERPINC1, SERPINB1 | LMNA 1161/4885POLB 2296/4885ALDH1A1 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.