Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6761545 | 0.84 | PKM (0.61) | PKMALDH1A1GPR55GAAMAPK1 | |
| SCHEMBL14380419 | 0.83 | PKM (0.56) | PKMALDH1A1GPR55GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL5065529 | 0.82 | PKM (0.55) | PKMALDH1A1GPR55GAAMAPK1 | |
| SCHEMBL6667999 | 0.77 | PKM (0.63) | PKMALDH1A1GPR55GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL6759662 | 0.76 | PKM (0.51) | PKMALDH1A1GPR55GAAMAPK1 | |
| SCHEMBL6667782 | 0.74 | PKM (0.49) | PKMALDH1A1GPR55GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL6757352 | 0.73 | PKM (0.48) | PKMALDH1A1GPR55GAAMAPK1 | |
| SCHEMBL16313533 | 0.73 | GPR55 (0.58) | PKMALDH1A1GPR55GAAMAPK1 | |
| SCHEMBL6668632 | 0.73 | HDAC4 (0.40) | ALDH1A1LMNAMEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL5070536 | 0.71 | PKM (0.48) | PKMALDH1A1GPR55GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | TANABE SEIYAKU CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106635-A1 | having small-conductance potassium channel (SK) blocking activity | KCNN1, KCNN2, KCNN3 | PKM 204/4885ALDH1A1 1229/4885GPR55 1996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.