Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HRAS | P01112 | 1/20 | 0.56 |
| ▸ | KRAS | P01116 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763704 | 0.89 | ALDH1A1 (0.51) | HTTMEN1KMT2AALDH1A1HRAS | |
| SCHEMBL6763749 | 0.84 | PPARG (0.63) | HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6763717 | 0.82 | ALDH1A1 (0.44) | HTTMEN1KMT2AALDH1A1HRAS | |
| SCHEMBL6763745 | 0.81 | GRIA4 (0.48) | HTTMEN1KMT2AALDH1A1HRAS | |
| SCHEMBL6763747 | 0.81 | ALDH1A1 (0.47) | HTTMEN1KMT2AALDH1A1HRAS | |
| SCHEMBL6765784 | 0.81 | RAB9A (0.63) | MEN1KMT2APOLBSMN1; SMN2CA1 | |
| SCHEMBL6571967 | 0.81 | PTGS2 (0.45) | HTTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6762788 | 0.81 | CA1 (0.45) | HTTMEN1KMT2AALDH1A1HRAS | |
| SCHEMBL25132140 | 0.80 | HTT (1.00) | HTTMEN1KMT2AALDH1A1HRAS | |
| SCHEMBL6759300 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | HTT 1694/4885MEN1 4050/4885KMT2A 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.