Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.63 |
| ▸ | NPC1 | O15118 | 10/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759300 | 0.85 | ALDH1A1 (0.54) | RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL6763704 | 0.84 | ALDH1A1 (0.51) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6759313 | 0.82 | MTNR1A (0.48) | SMN1; SMN2HPGDKMT2AMAPTMTNR1A | |
| SCHEMBL6763749 | 0.81 | PPARG (0.63) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6762092 | 0.81 | HTT (0.66) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL6763717 | 0.79 | ALDH1A1 (0.44) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6571967 | 0.78 | PTGS2 (0.45) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL6763745 | 0.77 | GRIA4 (0.48) | SMN1; SMN2MEN1KMT2ACA1CA2 | |
| SCHEMBL6763747 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL6761044 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2AALOX5MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | RAB9A 2451/4885NPC1 2223/4885SMN1; SMN2 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.