Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779739 | 0.91 | ELANE (0.37) | ALDH1A1CYP3A4 | |
| SCHEMBL6760712 | 0.87 | ELANE (0.35) | ALDH1A1 | |
| SCHEMBL6760481 | 0.79 | CYP3A4 (0.36) | CHRM2CHRM1CYP3A4ADRA2AADRA2C | |
| SCHEMBL15238219 | 0.77 | CHRM2 (0.65) | CHRM2CHRM1ADRB2ADRA1A | |
| SCHEMBL6757054 | 0.70 | CHRM2 (0.52) | ALOX15ALDH1A1CHRM2CHRM1CYP3A4 | |
| SCHEMBL6760704 | 0.70 | CHRM3 (0.30) | — | |
| SCHEMBL6757095 | 0.69 | KIF11 (0.34) | ALOX15ALDH1A1CHRM1CYP3A4DRD2 | |
| SCHEMBL6761109 | 0.69 | CHRM2 (0.53) | ALOX15ALDH1A1CHRM2CHRM1CYP3A4 | |
| SCHEMBL2166329 | 0.64 | CHRM2 (0.81) | ALOX15ALDH1A1CHRM2CHRM1CYP3A4 | |
| SCHEMBL2166331 | 0.64 | CHRM2 (0.81) | ALOX15ALDH1A1CHRM2CHRM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | SCHWARZ PHARMA AG | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186061-A1 | Novel derivatives of 3,3-diphenylpropylamines | ADRB3, ADRA1D, TNNC1 | ALOX15 2393/4885ALDH1A1 928/4885CHRM2 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.