Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760712 | 0.93 | ELANE (0.35) | ELANEALDH1A1 | |
| SCHEMBL6762097 | 0.91 | ALOX15 (0.39) | ALDH1A1CYP3A4 | |
| SCHEMBL6760481 | 0.78 | CYP3A4 (0.36) | ELANECYP3A4 | |
| SCHEMBL3779737 | 0.71 | ELANE (0.44) | ELANEALDH1A1CYP3A4LMNAHIF1A | |
| SCHEMBL15238219 | 0.69 | CHRM2 (0.65) | LMNA | |
| SCHEMBL6760704 | 0.69 | CHRM3 (0.30) | — | |
| SCHEMBL6757095 | 0.68 | KIF11 (0.34) | ALDH1A1CYP3A4LMNAHIF1A | |
| SCHEMBL2167092 | 0.67 | CHRM2 (0.64) | ELANEALDH1A1LMNA | |
| SCHEMBL13313847 | 0.65 | ESRRG (0.37) | ELANEALDH1A1CYP3A4LMNAHIF1A | |
| SCHEMBL6760711 | 0.64 | CHRM2 (0.42) | ELANEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855230-B2 | Derivatives of 3,3-diphenylpropylamines | UCB PHARMA GMBH (DE) | 2010-12-21 | — | — | US | disclosed |
| US-20090042981-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042981-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | ADRB3, TNNI3, ADRB2 | ELANE 4204/4885ALDH1A1 1088/4885CYP3A4 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.