Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766605 | 0.88 | ESR1 (0.54) | SLC6A3TSHRMAPTHSD17B10KDM4E | |
| SCHEMBL6759838 | 0.86 | KMT2A (0.50) | SLC6A3TSHRMAPTHSD17B10KDM4E | |
| SCHEMBL6761214 | 0.83 | SLC6A3 (0.58) | SLC6A3TSHRMAPTHSD17B10KDM4E | |
| SCHEMBL6759803 | 0.83 | TDP1 (0.54) | SLC6A3TSHRMAPTMAPK1KMT2A | |
| SCHEMBL6760438 | 0.83 | LMNA (0.56) | SLC6A3TSHRMAPTHSD17B10KDM4E | |
| SCHEMBL6761423 | 0.81 | TSHR (0.52) | TSHRMAPTHSD17B10KDM4EMAPK1 | |
| SCHEMBL6766253 | 0.80 | TSHR (0.63) | SLC6A3TSHRMAPTKMT2AMEN1 | |
| SCHEMBL6759718 | 0.80 | TSHR (0.53) | TSHRMAPTHSD17B10KDM4EMAPK1 | |
| SCHEMBL6763875 | 0.79 | ALDH1A1 (0.54) | TSHRMAPTHSD17B10KDM4EMAPK1 | |
| SCHEMBL6761470 | 0.79 | ALDH1A1 (0.54) | TSHRMAPTHSD17B10KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | VALENZUELA CORTES CARMEN MARIA (CL) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040247698-A1 | Erectile Dysfunction Treatment | PDE3A, PDE3B, PDE12 | SLC6A3 414/4885TSHR 4615/4885MAPT 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.