SCHEMBL676344

SCHEMBL676344

CNc1cccc(N2C(=O)c3ccc(C(C)=O)cc3C2=O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.60
▸ TDP1 Q9NUW8 1/20 0.60
▸ CTDSP1 Q9GZU7 1/20 0.56
▸ MAPK1 P28482 1/20 0.55
▸ HSD17B10 Q99714 1/20 0.54
▸ RAB9A P51151 1/20 0.52
▸ ALDH1A1 P00352 3/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ MEN1 O00255 3/20 0.51
▸ KMT2A Q03164 3/20 0.51
▸ GFER P55789 1/20 0.51
▸ S100B P04271 1/20 0.51
▸ HPGD P15428 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ ESR1 P03372 1/20 0.47
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ CA4 P22748 1/20 0.46
▸ CA9 Q16790 1/20 0.46
▸ ENPP2 Q13822 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12112142 0.85 POLB (0.56) POLBTDP1CTDSP1MAPK1HSD17B10
SCHEMBL13533871 0.85 POLB (0.60) POLBTDP1CTDSP1MAPK1RAB9A
SCHEMBL22681682 0.81 POLB (0.55) POLBTDP1CTDSP1MAPK1ALDH1A1
SCHEMBL675762 0.80 POLB (0.54) POLBCTDSP1MAPK1RAB9AALDH1A1
SCHEMBL675768 0.79 MEN1 (0.57) POLBRAB9AALDH1A1MEN1KMT2A
SCHEMBL14016924 0.78 CA9 (0.64) POLBALDH1A1MEN1KMT2AGFER
SCHEMBL12371878 0.78 KMT2A (0.55) POLBTDP1CTDSP1MAPK1HSD17B10
SCHEMBL12112145 0.78 S100B (0.83) POLBTDP1CTDSP1MAPK1HSD17B10
SCHEMBL11246411 0.77 POLB (0.77) POLBTDP1CTDSP1ALDH1A1SMN1; SMN2
SCHEMBL14947001 0.76 MAPK1 (0.81) POLBTDP1CTDSP1MAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11685829-B2 Process for preparing particles of aromatic polymers, particles obtainable by said process and their uses SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-06-27 — — US disclosed
US-11685829-B2 Process for preparing particles of aromatic polymers, particles obtainable by said process and their uses SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-06-27 — — US disclosed
EP-3389877-B1 MULTILAYER ASSEMBLY SOLVAY SPECIALTY POLYMERS IT (IT) 2023-04-26 — — EP disclosed
US-11376815-B2 Multilayer assembly SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2022-07-05 — — US disclosed
US-11352499-B2 Sulfone polymer composition SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-07 — — US disclosed
EP-3752562-B1 FLUOROELASTOMER CURABLE COMPOSITION SOLVAY SPECIALTY POLYMERS IT (IT) 2022-01-12 — — EP disclosed
US-20210214543-A1 FLUOROELASTOMER CURABLE COMPOSITION SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2021-07-15 — — US disclosed
US-20210139650-A1 END-CAPPED POLY(ARYL ETHER SULFONE) POLYMERS, POLY(ARYL ETHER SULFONE) BLOCK COPOLYMERS, AND CORRESPONDING SYNTHESIS METHODS SOLVAY SPECIALITY POLYMERS USA, LLC 2021-05-13 — — US disclosed
EP-3523365-B1 POROUS ARTICLE COMPRISING A POLYMER AND AN ADDITIVE, PROCESSES FOR THEIR PREPARATION AND USE THEREOF SOLVAY SPECIALTY POLYMERS USA (US) 2021-04-07 — — EP disclosed
US-20200362177-A1 FLUOROPOLYMER COMPOSITION SOLVAY SPECIALTY POLYMERS IT (US) 2020-11-19 — — US disclosed
US-20090069507-A1 Aromatic Polyimide Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-03-12 — — US disclosed
US-20090069507-A1 Aromatic Polyimide Composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2009-03-12 — — US disclosed
US-20090018244-A1 Water-Based Fluoropolymer Composition SOLVAY SOLEXIS, S.P.A. (IT) 2009-01-15 — — US disclosed
US-20090018244-A1 Water-Based Fluoropolymer Composition SOLVAY SOLEXIS, S.P.A. (IT) 2009-01-15 — — US disclosed
US-20080275162-A1 Ptfe-Based Compositions SOLVAY (SOCIETE ANONYME) (BE) 2008-11-06 — — US disclosed
US-20080275162-A1 Ptfe-Based Compositions SOLVAY (SOCIETE ANONYME) (BE) 2008-11-06 — — US disclosed
US-20080014423-A1 Fluoropolymer Tape, Article Comprising a Fluoropolymer Tape and Process for Manufacturing a Fluoropolymer Tape SOLVAY (SOCIETE ANONYMW (BE) 2008-01-17 — — US disclosed
US-20080014423-A1 Fluoropolymer Tape, Article Comprising a Fluoropolymer Tape and Process for Manufacturing a Fluoropolymer Tape SOLVAY (SOCIETE ANONYMW (BE) 2008-01-17 — — US disclosed
US-20070222108-A1 Aromatic Polyimide Composition and Articles Manufactured Therefrom SOLVAY (SOCIETE ANONYME) (BE) 2007-09-27 — — US disclosed
US-20070222108-A1 Aromatic Polyimide Composition and Articles Manufactured Therefrom SOLVAY (SOCIETE ANONYME) (BE) 2007-09-27 — — US disclosed
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