Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16125853 | 0.90 | KMT2A (0.46) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL13533871 | 0.81 | POLB (0.60) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL676344 | 0.78 | POLB (0.60) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL14944810 | 0.78 | POLB (0.67) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL14944811 | 0.78 | MEN1 (0.71) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL675762 | 0.76 | POLB (0.54) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL28885894 | 0.76 | CA1 (0.56) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL29993644 | 0.76 | CA1 (0.56) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL675768 | 0.75 | MEN1 (0.57) | KMT2AMEN1POLBALDH1A1HPGD | |
| SCHEMBL13236544 | 0.75 | ESR1 (0.40) | KMT2AMEN1POLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7993632-B2 | Cosmetic formulation containing at least one thickener selected from associative polymers | L'OREAL S.A. (FR) | 2011-08-09 | — | — | US | disclosed |
| US-7820151-B2 | Composition for coating keratin fibers, comprising at least one tacky wax and fibers | L'OREAL S.A. (FR) | 2010-10-26 | — | — | US | disclosed |
| US-20100158962-A1 | CHARGING/SEPARATING COSMETIC MAKEUP COMPOSITIONS FOR KERATIN FIBERS | L'OREAL S.A. | 2010-06-24 | — | — | US | disclosed |
| US-20080050329-A1 | Composition for Coating Keratin Fibres Comprising a Block Polymer and Fibres | L'OREAL S.A. (FR) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158962-A1 | CHARGING/SEPARATING COSMETIC MAKEUP COMPOSITIONS FOR KERATIN FIBERS | KRT18, CUTA, DSG1 | KMT2A 752/4885MEN1 3352/4885POLB 372/4885 |
| US-20080050329-A1 | Composition for Coating Keratin Fibres Comprising a Block Polymer and Fibres | KRT18, KIF5B, MARK3 | KMT2A 448/4885MEN1 2872/4885POLB 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.