Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759186 | 0.86 | ESR1 (0.51) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL6761165 | 0.81 | ACHE (0.38) | — | |
| SCHEMBL6759206 | 0.80 | MEN1 (0.38) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL4606562 | 0.80 | MEN1 (0.41) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL17042474 | 0.79 | ESR1 (0.45) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL28207465 | 0.79 | ESR1 (0.45) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL6759169 | 0.79 | HSP90AA1 (0.41) | MEN1KMT2APOLBGAAGFER | |
| SCHEMBL29485576 | 0.77 | MEN1 (0.57) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL6762631 | 0.77 | ESR1 (0.41) | ESR1ESR2MEN1KMT2APOLB | |
| SCHEMBL1237159 | 0.77 | MEN1 (0.57) | ESR1ESR2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720460-B2 | FORMING HEAT RESISTANT, MECHANICAL STRENGTH POLYMER ADDITIVES; ACID CATALYZED REACTION OF ADAMANTANE DIOL OR TRIOL WITH PHENOLIC DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| US-20030187307-A1 | Hydroxyphenyl adamantanes and process for the production of the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1336597-A1 | Hydroxyphenyl adamantanes and process for the production of the same | Honshu Chemical Industry Co., Ltd. (JP) | 2003-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187307-A1 | Hydroxyphenyl adamantanes and process for the production of the same | CYP8B1, DHPS, P4HA1 | ESR1 4719/4885ESR2 4436/4885MEN1 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.