Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764208 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNANPSR1NPC1 | |
| SCHEMBL6760065 | 0.93 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNANR1D1USP30 | |
| SCHEMBL6760068 | 0.93 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNANR1D1USP30 | |
| SCHEMBL27178869 | 0.78 | PDK2 (0.51) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL24628140 | 0.77 | USP30 (0.52) | NR1D1USP30JAK2JAK1 | |
| SCHEMBL29772918 | 0.77 | USP30 (0.52) | NR1D1USP30JAK2JAK1 | |
| SCHEMBL16698519 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNANR1D1USP30 | |
| SCHEMBL16391136 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNANR1D1USP30 | |
| SCHEMBL16370671 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNANR1D1USP30 | |
| SCHEMBL6764205 | 0.76 | NPBWR1 (0.43) | ALDH1A1MAPTLMNAUSP30SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | LABORATORIOS VITA, S.A. (ES) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | OXA1L, Q6ZSR9, PGC | ALDH1A1 1970/4885MAPT 3693/4885LMNA 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.