SCHEMBL6764205

SCHEMBL6764205

CC(C)(C)OC(=O)N1CCCCC(NCc2ccc([N+](=O)[O-])cc2F)C1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPBWR1 P48145 1/20 0.43
MCHR1 Q99705 1/20 0.43
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
USP30 Q70CQ3 2/20 0.42
GPR119 Q8TDV5 4/20 0.40
SCN9A Q15858 1/20 0.40
ANO1 Q5XXA6 2/20 0.39
SLC6A9 P48067 1/20 0.39
SLC6A5 Q9Y345 1/20 0.39
TRPV3 Q8NET8 1/20 0.39
DPP4 P27487 1/20 0.39
DRD2 P14416 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6760062 0.94 ALDH1A1 (0.45) ALDH1A1LMNAMAPTUSP30GPR119
SCHEMBL17140249 0.81 ALDH1A1 (0.49) NPBWR1MCHR1ALDH1A1LMNAMAPT
SCHEMBL2088384 0.78 ALDH1A1 (0.50) ALDH1A1LMNAMAPTUSP30GPR119
SCHEMBL6761275 0.77 F10 (0.45) LMNAUSP30
SCHEMBL31043946 0.77 LMNA (0.52) ALDH1A1LMNAMAPTGPR119SCN9A
SCHEMBL6760101 0.77 USP30 (0.51) ALDH1A1MAPTUSP30GPR119ANO1
SCHEMBL6764207 0.76 ALDH1A1 (0.47) ALDH1A1LMNAMAPTUSP30SLC6A9
SCHEMBL6764208 0.76 ALDH1A1 (0.47) ALDH1A1LMNAMAPTUSP30SLC6A9
SCHEMBL30523709 0.76 GPR119 (0.52) ALDH1A1GPR119DPP4
SCHEMBL20766541 0.76 GPR119 (0.52) ALDH1A1GPR119DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040147545-A1 Derivatives of oxazolidinones as antibacterial agents LABORATORIOS VITA, S.A. (ES) 2004-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147545-A1 Derivatives of oxazolidinones as antibacterial agents OXA1L, Q6ZSR9, PGC NPBWR1 3843/4885MCHR1 4199/4885ALDH1A1 1970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.