Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 16/20 | 0.47 |
| ▸ | FEN1 | P39748 | 15/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163208 | 0.84 | ALOX5AP (0.45) | ALOX5APFEN1 | |
| SCHEMBL7107058 | 0.83 | ALOX5AP (0.52) | ALOX5APFEN1 | |
| SCHEMBL890585 | 0.79 | ALOX5AP (0.65) | ALOX5APFEN1 | |
| Hydrochloric Acid SCHEMBL6175800 | 0.78 | ALOX5AP (0.64) | ALOX5APFEN1 | |
| SCHEMBL11224124 | 0.75 | MEN1 (0.61) | — | |
| SCHEMBL17507368 | 0.72 | MEN1 (0.54) | ALOX5APFEN1JAK2 | |
| SCHEMBL24429413 | 0.72 | CCR2 (0.59) | CNR1 | |
| SCHEMBL3779908 | 0.72 | CNR1 (0.44) | JAK2CNR1 | |
| SCHEMBL18498795 | 0.72 | CNR1 (0.42) | CNR1 | |
| SCHEMBL22648438 | 0.72 | MCL1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-6720317-B1 | 1-NAPHTH-2-YL-1H-PYRAZOLE-5-(4-AMIDINOPHENYL)CARBOXYAMIDE, MULTIPLY SUBSTITUTED; NON AMIDINO ANTICOAGULANTS; HEMOSTATIC AGENTS | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-13 | — | — | US | disclosed |
| US-6686368-B1 | Inhibitors of factor Xa | MILLENNIUM PAHRMACEUTICALS, INC. | 2004-02-03 | — | — | US | disclosed |
| US-6632815-B2 | Show selectivity for factor Xa versus other proteases of coagulation or the fibrinolytic cascades | MILLENNIUM PHARMACEUTICALS, INC. | 2003-10-14 | — | — | US | disclosed |
| US-20020091116-A1 | Show selectivity for factor Xa versus other proteases of coagulation or the fibrinolytic cascades | MILLENNIUM PHARMACEUTICALS, INC. | 2002-07-11 | — | — | US | disclosed |
| EP-1216231-A2 | INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019798-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2001-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091116-A1 | Show selectivity for factor Xa versus other proteases of coagulation or the fibrinolytic cascades | SERPINC1, TFPI, F2 | ALOX5AP 948/4885FEN1 507/4885JAK2 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.