SCHEMBL3779908

SCHEMBL3779908

CC(C)(C)NS(=O)(=O)c1ccc(Cl)cc1I

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.44
ALDH1A1 P00352 2/20 0.44
CCR2 P41597 4/20 0.42
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
NSD2 O96028 2/20 0.38
TRPV4 Q9HBA0 1/20 0.38
PARG Q86W56 1/20 0.37
MCL1 Q07820 2/20 0.37
ALPG P10696 1/20 0.36
JAK2 O60674 1/20 0.36
TSHR P16473 1/20 0.36
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4184746 0.82 CA12 (0.50) CNR1CCR2HPGDLMNATRPV4
SCHEMBL21962890 0.81 ALDH1A1 (0.46) ALDH1A1MAPTSMN1; SMN2HPGDKDM4E
SCHEMBL24429413 0.79 CCR2 (0.59) CNR1ALDH1A1CCR2
SCHEMBL22648438 0.79 MCL1 (0.59) ALDH1A1MAPTHPGDMEN1RAB9A
SCHEMBL1790814 0.77 CNR1 (0.51) CNR1ALDH1A1CCR2MAPTSMN1; SMN2
SCHEMBL6210760 0.77 CNR1 (0.45) CNR1ALDH1A1CCR2MAPTSMN1; SMN2
SCHEMBL6210755 0.77 CNR1 (0.43) CNR1ALDH1A1CCR2MAPTSMN1; SMN2
SCHEMBL18498795 0.76 CNR1 (0.42) CNR1ALDH1A1CCR2MAPTSMN1; SMN2
SCHEMBL4185547 0.76 L3MBTL1 (0.61) CNR1ALDH1A1CCR2SMN1; SMN2KDM4E
SCHEMBL20451442 0.76 SLC22A12 (0.46) CNR1ALDH1A1CCR2MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP claimed
US-7855166-B2 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2010-12-21 US disclosed
EP-1877380-A1 SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2008-01-16 EP disclosed
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2006-11-16 US disclosed
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP disclosed
WO-2006114221-A1 SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2006-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds TST, CBR3, MYB CNR1 1768/4885ALDH1A1 1134/4885CCR2 4306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.