Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768499 | 0.84 | DNM2 (0.38) | DNM2 | |
| SCHEMBL8599872 | 0.83 | NUDT1 (0.36) | DNM2NUDT1 | |
| SCHEMBL8599974 | 0.71 | DNM2 (0.37) | DNM2NUDT1 | |
| SCHEMBL6404443 | 0.71 | DNM2 (0.37) | DNM2NUDT1 | |
| SCHEMBL7518385 | 0.69 | DNM2 (0.44) | DNM2NUDT1 | |
| SCHEMBL7712163 | 0.63 | DNM2 (0.47) | DNM2NUDT1 | |
| SCHEMBL8599188 | 0.62 | KMT2A (0.33) | — | |
| SCHEMBL9182270 | 0.61 | NUDT1 (0.66) | DNM2NUDT1 | |
| SCHEMBL7633778 | 0.60 | PGK1 (0.36) | — | |
| SCHEMBL8598479 | 0.60 | NUDT1 (0.36) | NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103216-A1 | Administering topically a tyrosinase activity-stimulating amount of a 6-substituted pyrimidine 3-oxide | PRUCHE FRANCIS (FR) | 2002-08-01 | — | — | US | claimed |
| EP-0829260-B1 | Use of at least one pyrimidine derivative substituted in position 6 as stimulant of tyrosinase | OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6380263-B1 | ADMINISTERING TO HUMAN EFFECTIVE TYROSINASE ACTIVITY-STIMULATING AMOUNT OF AT LEAST ONE 6-SUBSTITUTED PYRIMIDINE 3-OXIDE COMPOUND FOR PROMOTING PIGMENTATION OF THE SKIN AND/OR HAIR | SOCIETE L'OREAL (FR) | 2002-04-30 | — | — | US | claimed |
| US-6726940-B2 | STIMULATING MELANOGENESIS. | SOCIETE L'OREAL S.A. (FR) | 2004-04-27 | — | — | US | disclosed |
| US-20020122812-A1 | Use of at least one extract of the genus chrysanthemum for assisting skin and/or hair pigmentation | MARTIN RICHARD (FR) | 2002-09-05 | — | — | US | disclosed |
| US-20020103216-A1 | Administering topically a tyrosinase activity-stimulating amount of a 6-substituted pyrimidine 3-oxide | PRUCHE FRANCIS (FR) | 2002-08-01 | — | — | US | disclosed |
| US-6380263-B1 | ADMINISTERING TO HUMAN EFFECTIVE TYROSINASE ACTIVITY-STIMULATING AMOUNT OF AT LEAST ONE 6-SUBSTITUTED PYRIMIDINE 3-OXIDE COMPOUND FOR PROMOTING PIGMENTATION OF THE SKIN AND/OR HAIR | SOCIETE L'OREAL (FR) | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020122812-A1 | Use of at least one extract of the genus chrysanthemum for assisting skin and/or hair pigmentation | TYR, CUTA, MC1R | DNM2 2271/4885NUDT1 3616/4885 |
| US-20020103216-A1 | Administering topically a tyrosinase activity-stimulating amount of a 6-substituted pyrimidine 3-oxide | TYR, TH, MC1R | DNM2 3991/4885NUDT1 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.