SCHEMBL9004476

SCHEMBL9004476

BrCc1ccc(/C=C/c2ccc(CBr)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
TUBB1 Q9H4B7 1/20 0.35
NFE2L2 Q16236 2/20 0.35
CYP19A1 P11511 2/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9004477 1.00 TRPA1 (0.48) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL6764667 0.90 ALDH1A1 (0.47) TRPA1ALDH1A1TSHRTUBB1MAOA
SCHEMBL8886584 0.90 TRPA1 (0.59) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL13978538 0.90 TRPA1 (0.59) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL6474481 0.90 TRPA1 (0.59) TRPA1ALDH1A1TSHRCES2CES1
SCHEMBL6764664 0.90 ALDH1A1 (0.47) TRPA1ALDH1A1TSHRTUBB1MAOA
SCHEMBL8885030 0.88 NFE2L2 (0.54) ALOX5PTGS1PTGS2NFE2L2
SCHEMBL26316677 0.88 NFE2L2 (0.52) ALOX5PTGS1PTGS2TUBB1NFE2L2
SCHEMBL11527604 0.88 AHR (0.52) TRPA1ALDH1A1TSHRALOX5PTGS1
SCHEMBL11527600 0.88 AHR (0.52) TRPA1ALDH1A1TSHRALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014027964-A1 UNIVERSAL BIOSENSING AND BIOASSAY DEVICES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2014-02-20 WO disclosed
US-8614021-B2 Agents for enhanced charge transport across microbial membranes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2013-12-24 US disclosed
US-20120264649-A1 AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-10-18 US disclosed
US-20120264649-A1 AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-10-18 US disclosed
US-20120264649-A1 AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-10-18 US disclosed
EP-0442097-B1 Poly(arylenevinylene siloxanes) CONSORTIUM ELEKTROCHEM IND (DE) 1996-10-09 EP disclosed
US-5185419-A POLY(ARYLENEVINYLENESILOXANES) COMPOUNDS CONSORTIUM FUR ELEKTROCHEMISCHE GMBH (DE) 1993-02-09 US disclosed
EP-0442097-A2 Poly(arylenevinylene siloxanes) Consortium für elektrochemische Industrie GmbH (DE) 1991-08-21 EP disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed