Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567619 | 0.80 | KMT2A (0.65) | RAB9AGAANPC1SMN1; SMN2TRPV1 | |
| SCHEMBL6763008 | 0.80 | CXCR2 (0.67) | RAB9AGAANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6760901 | 0.80 | EPHX2 (0.56) | RAB9AGAANPC1SMN1; SMN2TRPV1 | |
| SCHEMBL6764064 | 0.80 | P2RX1 (0.64) | RAB9AGAANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1463349 | 0.79 | GSK3A (0.66) | RAB9AGAANPC1SMN1; SMN2TRPV1 | |
| SCHEMBL3704175 | 0.77 | CXCR2 (0.67) | RAB9AGAANPC1SMN1; SMN2TRPV1 | |
| SCHEMBL16127720 | 0.77 | GAA (0.62) | GAASMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL6763103 | 0.77 | CYP3A4 (0.61) | GAASMN1; SMN2TRPV1ALDH1A1LMNA | |
| SCHEMBL27430704 | 0.76 | TSHR (0.55) | RAB9AGAANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17978458 | 0.76 | LPAR1 (0.59) | LPAR1RAB9AGAANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063742-A1 | Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity | NEUROSEARCH A/S (DK) | 2004-04-01 | — | — | US | claimed |
| US-20040063742-A1 | Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity | NEUROSEARCH A/S (DK) | 2004-04-01 | — | — | US | disclosed |