Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764064 | 0.90 | P2RX1 (0.64) | EPHX2RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL1463349 | 0.86 | GSK3A (0.66) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL4350115 | 0.85 | BAZ1A (0.65) | EPHX2BAZ1ARAB9AMAPTMEN1 | |
| SCHEMBL16782003 | 0.85 | MAPT (0.70) | EPHX2RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL6763103 | 0.84 | CYP3A4 (0.61) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1463448 | 0.83 | MAPT (0.71) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL6763008 | 0.82 | CXCR2 (0.67) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL6765116 | 0.80 | LPAR1 (0.60) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL8401870 | 0.78 | TMPRSS4 (0.81) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL3476076 | 0.77 | RAF1 (0.61) | EPHX2BAZ1AMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063742-A1 | Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity | NEUROSEARCH A/S (DK) | 2004-04-01 | — | — | US | claimed |
| US-20040063742-A1 | Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity | NEUROSEARCH A/S (DK) | 2004-04-01 | — | — | US | disclosed |