Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.44 |
| ▸ | CNR2 | P34972 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25307327 | 0.87 | MAPT (0.45) | ALDH1A1TAS2R14CNR2LMNATSHR | |
| SCHEMBL12205672 | 0.84 | CNR2 (0.56) | TAS2R14CNR2MAPTPKM | |
| SCHEMBL30701971 | 0.81 | CNR2 (0.46) | TAS2R14CNR2LMNATSHRHTT | |
| SCHEMBL27192066 | 0.81 | CNR2 (0.46) | TAS2R14CNR2LMNATSHRHTT | |
| SCHEMBL3218808 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TAS2R14CNR2LMNATSHR | |
| SCHEMBL6769019 | 0.80 | TAS2R14 (0.58) | ALDH1A1TAS2R14CNR2LMNAMAPT | |
| SCHEMBL1705206 | 0.79 | CNR2 (0.60) | TAS2R14CNR2LMNATSHRHTT | |
| SCHEMBL1411858 | 0.79 | CNR2 (0.50) | TAS2R14CNR2MAPTPKM | |
| SCHEMBL12451189 | 0.79 | CNR2 (0.50) | TAS2R14CNR2MAPTPKM | |
| SCHEMBL11497159 | 0.78 | CNR2 (0.63) | ALDH1A1TAS2R14CNR2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016112088-A1 | ARYLOXYACETYLINDOLES AND ANALOGS AS ANTIBIOTIC TOLERANCE INHIBITORS | SPERO THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | WO | disclosed |
| WO-2016112088-A1 | ARYLOXYACETYLINDOLES AND ANALOGS AS ANTIBIOTIC TOLERANCE INHIBITORS | SPERO THERAPEUTICS, INC. (US) | 2016-07-14 | — | — | WO | disclosed |
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |