Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709377 | 0.90 | TAS2R14 (0.56) | TAS2R14CA12CA1CA2CA4 | |
| SCHEMBL11497159 | 0.85 | CNR2 (0.63) | TAS2R14ALDH1A1POLBCNR2MAPT | |
| SCHEMBL12205672 | 0.84 | CNR2 (0.56) | TAS2R14POLBCNR2MAPTPKM | |
| SCHEMBL30701971 | 0.80 | CNR2 (0.46) | TAS2R14CNR2LMNA | |
| SCHEMBL27192066 | 0.80 | CNR2 (0.46) | TAS2R14CNR2LMNA | |
| SCHEMBL25307327 | 0.80 | MAPT (0.45) | TAS2R14CA12CA1CA2CA4 | |
| SCHEMBL22451561 | 0.80 | TAS2R14 (0.64) | TAS2R14CA12CA1CA2CA4 | |
| SCHEMBL6765985 | 0.80 | ALDH1A1 (0.44) | TAS2R14ALDH1A1CNR2MAPTPKM | |
| SCHEMBL2986080 | 0.79 | CNR2 (0.43) | TAS2R14POLBCNR2MAPTPKM | |
| SCHEMBL1705734 | 0.79 | CNR2 (0.44) | TAS2R14CNR2MAPTPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |