SCHEMBL3218808

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4600615	0.85	ALDH1A1 (0.36)	ALDH1A1TAS2R14LMNASMN1; SMN2TSHR
	SCHEMBL15495285	0.83	BMP1 (0.43)	ALDH1A1TAS2R14LMNASMN1; SMN2HTT
	SCHEMBL4601251	0.80	BMP1 (0.35)	ALDH1A1TAS2R14LMNASMN1; SMN2HTT
	SCHEMBL6765985	0.80	ALDH1A1 (0.44)	ALDH1A1TAS2R14LMNASMN1; SMN2TSHR
	SCHEMBL25307327	0.80	MAPT (0.45)	ALDH1A1TAS2R14LMNASMN1; SMN2TSHR
	SCHEMBL12205672	0.78	CNR2 (0.56)	TAS2R14MAPTCNR2
	SCHEMBL15056437	0.75	TAS2R14 (0.40)	ALDH1A1TAS2R14LMNASMN1; SMN2TSHR
	SCHEMBL30701971	0.74	CNR2 (0.46)	TAS2R14LMNATSHRHTTCNR2
	SCHEMBL27192066	0.74	CNR2 (0.46)	TAS2R14LMNATSHRHTTCNR2
	SCHEMBL31551717	0.73	LMNA (0.38)	ALDH1A1TAS2R14LMNASMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.