Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574024 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL6762132 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL6574412 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL6766036 | 0.77 | ITGB3 (0.42) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL6569900 | 0.74 | ITGB3 (0.41) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL6572891 | 0.73 | IDO1 (0.43) | ALDH1A1PSMB5SMN1; SMN2LMNAIDO1 | |
| SCHEMBL6573948 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL6571792 | 0.72 | PSMB5 (0.38) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL6571971 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL8360714 | 0.71 | ITGB3 (0.45) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | NAT1, CYP3A5, CYP3A7 | ALDH1A1 669/4885MAPT 449/4885GAA 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.