Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 5/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762132 | 0.91 | ALDH1A1 (0.40) | ITGB3ITGA2BALDH1A1MAPTGAA | |
| SCHEMBL8360714 | 0.88 | ITGB3 (0.45) | ITGB3ITGA2BALDH1A1MAPTGAA | |
| SCHEMBL6767048 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BALDH1A1MAPTGAA | |
| SCHEMBL6569900 | 0.84 | ITGB3 (0.41) | ITGB3ITGA2BALDH1A1MAPTGAA | |
| SCHEMBL6571971 | 0.82 | ALDH1A1 (0.39) | ITGB3ITGA2BALDH1A1MAPTGAA | |
| SCHEMBL6562025 | 0.80 | ITGB3 (0.36) | ITGB3ITGA2BSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6766013 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL6571927 | 0.76 | ALDH1A1 (0.47) | ITGB3ITGA2BALDH1A1MAPTGAA | |
| SCHEMBL6762390 | 0.75 | ALDH1A1 (0.46) | ITGB3ITGA2BALDH1A1MAPTGAA | |
| SCHEMBL6762406 | 0.73 | ITGB3 (0.40) | ITGB3ITGA2BF7F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | NAT1, CYP3A5, CYP3A7 | ITGB3 3024/4885ITGA2B 3453/4885ALDH1A1 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.