Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410216 | 0.86 | MTNR1A (0.44) | MTNR1AMTNR1BL3MBTL1ALDH1A1 | |
| SCHEMBL27698058 | 0.84 | MTNR1A (0.53) | MTNR1AMTNR1BNR1H2EPHX2NR1H4 | |
| SCHEMBL16410342 | 0.84 | MTNR1A (0.47) | MTNR1AMTNR1BRORC | |
| SCHEMBL12546275 | 0.84 | MTNR1A (0.44) | MTNR1AMTNR1BNR1H2EPHX2NR1H4 | |
| SCHEMBL27451229 | 0.84 | NR1H4 (0.48) | MTNR1AMTNR1BNR1H2EPHX2NR1H4 | |
| SCHEMBL16410352 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1BNR1H2GAAMAPT | |
| SCHEMBL16410202 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1BGAAMAPTALDH1A1 | |
| SCHEMBL28069959 | 0.83 | MTNR1A (0.48) | MTNR1AMTNR1BNR1H2GAAMAPT | |
| SCHEMBL2129842 | 0.81 | ALDH1A1 (0.50) | GAAMAPK1MAPTTSHRHTT | |
| SCHEMBL15821497 | 0.81 | KDM4E (0.42) | MTNR1AMTNR1BNR1H2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248897-A1 | Substituted N-acylaniline derivatives, the preparation thereof, and their use as pharmaceutical compositions | NAT1, CYP3A5, CYP3A7 | MTNR1A 283/4885MTNR1B 930/4885NR1H2 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.