Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410352 | 0.88 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1GAAGFER | |
| SCHEMBL7590349 | 0.85 | ALDH1A1 (0.49) | MTNR1AMTNR1BALDH1A1GAAGFER | |
| SCHEMBL6766157 | 0.83 | MTNR1A (0.45) | MTNR1AMTNR1BALDH1A1GAAGFER | |
| SCHEMBL16410216 | 0.82 | MTNR1A (0.44) | MTNR1AMTNR1BALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL16410342 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BRIPK1RORC | |
| SCHEMBL16410202 | 0.79 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1GAAKDM4E | |
| SCHEMBL5866843 | 0.79 | LOXL2 (0.46) | MTNR1AMTNR1BALDH1A1NR1H2LOXL2 | |
| SCHEMBL20424475 | 0.79 | MTNR1A (0.50) | MTNR1AMTNR1BALDH1A1GAAGFER | |
| SCHEMBL15432956 | 0.77 | SLC7A5 (0.48) | MTNR1AMTNR1BALDH1A1NR1H2LOXL2 | |
| SCHEMBL7591321 | 0.77 | MTNR1A (0.39) | MTNR1AMTNR1BALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555766-A | Aminomethyl-biaryl derivatives as complement factor D inhibitors and uses thereof | NOVARTIS AG | 2016-05-04 | — | — | CN | disclosed |