SCHEMBL676674

SCHEMBL676674

COc1cc(Cl)c(Br)cn1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NNMT P40261 1/20 0.37
LOX P28300 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35
GABRE P78334 1/20 0.35
GABRA6 Q16445 1/20 0.35
GABRG1 Q8N1C3 1/20 0.35
GABRG3 Q99928 1/20 0.35
GABRQ Q9UN88 1/20 0.35
MAPT P10636 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30954879 0.86 NNMT (0.37) NNMT
SCHEMBL15710933 0.83 NNMT (0.37) NNMTGABRPGABRDGABRA1GABRB1
SCHEMBL676690 0.80 NNMT (0.40) NNMTLOXLOXL2GABRPGABRD
SCHEMBL31124303 0.80 NNMT (0.40) NNMTLOXLOXL2GABRPGABRD
SCHEMBL29907269 0.77 NNMT (0.50) NNMTGABRPGABRDGABRA1GABRB1
SCHEMBL28015248 0.77 NPC1 (0.42) NNMTGABRPGABRDGABRA1GABRB1
SCHEMBL3573917 0.77 AXL (0.42) NNMTGABRPGABRDGABRA1GABRB1
SCHEMBL18659548 0.77 NNMT (0.46) NNMTLOXLOXL2GABRPGABRD
SCHEMBL364584 0.77 NNMT (0.50) NNMTGABRPGABRDGABRA1GABRB1
SCHEMBL31449583 0.76 OXTR (0.41) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036680-A Anti-fibrotic pyridones 英特穆恩公司 2026-05-15 CN disclosed
US-12595255-B2 Heteroaryl-substituted imidazole derivatives HOFFMANN-LA ROCHE INC. (US) 2026-04-07 US disclosed
EP-4678641-A1 QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF Shanghai Helioson Pharmaceutical Co., Ltd. (CN) 2026-01-14 EP disclosed
EP-4635949-A1 SUBSTITUTED TETRAHYDROCYCLOPENTYL[C]PYRROLE DERIVATIVE, PREPARATION METHOD, INTERMEDIATE AND USE THEREOF Jiangsu NHWA Pharmaceutical Co., Ltd (CN) 2025-10-22 EP disclosed
US-12421228-B2 Naphthyridine derivatives as PRC2 inhibitors Mirati Therapeutics, Inc. (US) 2025-09-23 US disclosed
US-20250282787-A1 SUBSTITUTED IMIDAZO[1,2-c]PYRIMIDINES AS PRC2 INHIBITORS Mirati Therapeutics, Inc. 2025-09-11 US disclosed
EP-4134364-B1 BROMODOMAIN INHIBITORS CELGENE QUANTICEL RES INC (US) 2025-07-30 EP disclosed
US-12371435-B2 Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors Mirati Therapeutics, Inc. (US) 2025-07-29 US disclosed
US-20250179082-A1 IMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES AS PRC2 INHIBITORS FOR TREATING CANCER Mirati Therapeutics, Inc. 2025-06-05 US disclosed
WO-2025096751-A1 MACROCYCLIC INHIBITORS OF ATP CITRATE LYASE ESPERION THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed
CN-102165961-A Bactericide composition and method of controlling plant disease ISHIHARA SANGYO KAISHA 2011-08-31 CN disclosed
EP-2338335-A1 Preparation of fungicidal benzoylpyridine derivatives ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-06-29 EP disclosed
CN-101822253-A The method of control of microbicide compositions and plant disease ISHIHARA SANGYO KAISHA 2010-09-08 CN disclosed
CN-100581362-C Bactericide composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA 2010-01-20 CN disclosed
US-20090247763-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-10-01 US disclosed
CN-101215260-A Method for preparing benzoylpyridine derivatices and salt thereof ISHIHARA SANGYO KAISHA (JP) 2008-07-09 CN disclosed
CN-101199274-A Bactericide composition and method for controlling plant disease ISHIHARA SANGYO KAISHA (JP) 2008-06-18 CN disclosed
CN-1874680-A bactericide composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA (JP) 2006-12-06 CN disclosed
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-08-31 US disclosed
EP-1679003-A1 BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247763-A1 FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES CBR3, CBR1, CNPY2 NNMT 1513/4885LOX 756/4885LOXL2 1864/4885
US-12371435-B2 Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors EZH2, BMI1, SUZ12 NNMT 1251/4885LOX 3548/4885LOXL2 3867/4885
US-20250282787-A1 SUBSTITUTED IMIDAZO[1,2-c]PYRIMIDINES AS PRC2 INHIBITORS EZH2, BMI1, SUZ12 NNMT 609/4885LOX 2753/4885LOXL2 3004/4885
US-20250179082-A1 IMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES AS PRC2 INHIBITORS FOR TREATING CANCER BMI1, EZH2, SUZ12 NNMT 647/4885LOX 2086/4885LOXL2 2477/4885
US-20060194849-A1 Fungicidal composition and method for controlling plant diseases CBR3, CNPY2, PAH NNMT 1528/4885LOX 756/4885LOXL2 1916/4885
US-12595255-B2 Heteroaryl-substituted imidazole derivatives CLIC1, CYP2B6, CYP2D6 NNMT 4285/4885LOX 1283/4885LOXL2 3045/4885
US-12421228-B2 Naphthyridine derivatives as PRC2 inhibitors BMI1, EZH2, SUZ12 NNMT 388/4885LOX 1843/4885LOXL2 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.