Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124303 | 1.00 | NNMT (0.40) | NNMTSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL28015248 | 0.82 | NPC1 (0.42) | NNMTSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL677208 | 0.82 | NNMT (0.50) | NNMTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL18659548 | 0.82 | NNMT (0.46) | NNMTSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL29513500 | 0.82 | GAA (0.42) | NNMTSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL25347088 | 0.82 | GAA (0.42) | NNMTSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL473660 | 0.81 | SMN1; SMN2 (0.37) | NNMTSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL6686702 | 0.80 | NPC1 (0.45) | NNMTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL24553502 | 0.80 | NNMT (0.41) | NNMTSMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL21737273 | 0.80 | P2RX3 (0.40) | NNMTSMN1; SMN2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3558298-B1 | ANTIDIABETIC SPIROCHROMAN COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2026-03-11 | — | — | EP | disclosed |
| US-10968232-B2 | Antidiabetic spirochroman compounds | MERCK SHARP & DOHME CORP. (US) | 2021-04-06 | — | — | US | disclosed |
| CN-112441967-A | Preparation method of methoxybenzene cry bacterial intermediate | 南北兄弟药业投资有限公司 | 2021-03-05 | — | — | CN | disclosed |
| US-20190337961-A1 | ANTIDIABETIC SPIROCHROMAN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2019-11-07 | — | — | US | disclosed |
| EP-3558298-A1 | ANTIDIABETIC SPIROCHROMAN COMPOUNDS | Merck Sharp & Dohme Corp. (US) | 2019-10-30 | — | — | EP | disclosed |
| WO-2018118670-A1 | ANTIDIABETIC SPIROCHROMAN COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |
| US-20170188579-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA (JP) | 2017-07-06 | — | — | US | disclosed |
| US-9655362-B2 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2017-05-23 | — | — | US | disclosed |
| CN-103478142-B | The method of control of microbicide compositions and plant disease | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2016-03-30 | — | — | CN | disclosed |
| EP-1679003-B1 | BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE | ISHIHARA SANGYO KAISHA (JP) | 2015-04-15 | — | — | EP | disclosed |
| US-20120135088-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20110280959-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-11-17 | — | — | US | disclosed |
| EP-2338335-A1 | Preparation of fungicidal benzoylpyridine derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-20090247763-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1679003-A1 | BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| US-20060089390-A1 | 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-04-27 | — | — | US | disclosed |
| EP-1559320-A1 | 3-BENZOYL-2,4,5-SUBSTITUTED PYRIDINE DERIVATIVES OR SALTS THEREOF AND BACTERICIDES CONTAINING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-6333341-B1 | TUMOR NECROSIS FACTOR, ANTIINFLAMMATORY AGENTS AND ANALGESICS | AMGEN INC. | 2001-12-25 | — | — | US | disclosed |
| US-6184237-B1 | Substituted pyridine compounds and methods of use | AMGEN INC. | 2001-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247763-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CBR1, CNPY2 | NNMT 1513/4885SMN1; SMN2 1901/4885GABRP 925/4885 |
| US-20120135088-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CNPY2, PAH | NNMT 1528/4885SMN1; SMN2 2015/4885GABRP 931/4885 |
| US-10968232-B2 | Antidiabetic spirochroman compounds | GPR119, GPR52, GPR55 | NNMT 4254/4885SMN1; SMN2 4528/4885GABRP 3070/4885 |
| US-20190337961-A1 | ANTIDIABETIC SPIROCHROMAN COMPOUNDS | GPR119, GPR52, GPR55 | NNMT 4254/4885SMN1; SMN2 4528/4885GABRP 3070/4885 |
| US-20110280959-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CNPY2, PAH | NNMT 1528/4885SMN1; SMN2 2015/4885GABRP 931/4885 |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | CBR3, CNPY2, PAH | NNMT 1528/4885SMN1; SMN2 2015/4885GABRP 931/4885 |
| US-20170188579-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CNPY2, PAH | NNMT 1528/4885SMN1; SMN2 2015/4885GABRP 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.