Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768472 | 0.86 | CYP2D6 (0.51) | CYP2D6MAOBMGLLHSP90AA1ALDH1A1 | |
| SCHEMBL6766055 | 0.81 | CASP6 (0.41) | CYP2D6MAOBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL6763490 | 0.81 | CYP2D6 (0.54) | CYP2D6MAOBHSP90AA1SMN1; SMN2TSHR | |
| SCHEMBL5780097 | 0.81 | KMT2A (0.37) | CYP2D6MAOBMGLLTSHRKMT2A | |
| SCHEMBL6766363 | 0.78 | CYP2D6 (0.47) | CYP2D6MAOBALDH1A1MEN1KMT2A | |
| SCHEMBL10633526 | 0.77 | KMT2A (0.50) | MAOBNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL5780049 | 0.77 | SLC5A2 (0.36) | CYP2D6MGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6763578 | 0.77 | CYP2D6 (0.50) | CYP2D6MAOBNPC1RAB9AALDH1A1 | |
| SCHEMBL6766166 | 0.76 | CYP2D6 (0.40) | CYP2D6MAOBALDH1A1HPGDMEN1 | |
| SCHEMBL5781166 | 0.75 | HTR7 (0.46) | MAOBRAB9ASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | claimed |
| US-6825192-B1 | NON-N-METHYL-D-ASPARTATE (NON- NMDA) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTIC ACTION, FOR EXAMPLE 2-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC ACID (AMPA) RECEPTOR ANTAGONISTIC ACTION | EISAI CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1153922-A1 | HETERODIAZINONE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |