Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21558218 | 0.83 | GSR (0.52) | GSRCHRM2CHRM4CHRM1DPP7 | |
| SCHEMBL20241158 | 0.81 | BHMT (0.44) | GSRCHRM2CHRM4CHRM1LMNA | |
| SCHEMBL20243480 | 0.81 | BHMT (0.44) | GSRCHRM2CHRM4CHRM1LMNA | |
| SCHEMBL20243486 | 0.81 | BHMT (0.44) | GSRCHRM2CHRM4CHRM1LMNA | |
| SCHEMBL23882001 | 0.80 | CES2 (0.47) | CHRM2CHRM4CHRM1CYP1A2TSHR | |
| SCHEMBL20243493 | 0.80 | CES2 (0.47) | CHRM2CHRM4CHRM1CYP1A2TSHR | |
| SCHEMBL23882002 | 0.80 | CES2 (0.47) | CHRM2CHRM4CHRM1CYP1A2TSHR | |
| SCHEMBL936123 | 0.80 | CES2 (0.47) | CHRM2CHRM4CHRM1CYP1A2TSHR | |
| SCHEMBL28187149 | 0.76 | CHRM2 (0.44) | GSRCHRM2CHRM4CHRM1GABRR3 | |
| SCHEMBL2750074 | 0.76 | LMNA (0.56) | GSRGABRR3GABRPGABRDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281337-A1 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL | AGAIN BIO APS (DK) | 2011-11-17 | — | — | US | disclosed |