Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6324127 | 0.99 | SIGMAR1 (0.41) | SIGMAR1SRCMMP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL6767719 | 0.91 | MMP2 (0.40) | SIGMAR1MMP3ALDH1A1PSEN1PSEN2 | |
| SCHEMBL6324360 | 0.91 | SIGMAR1 (0.42) | SIGMAR1SRCMMP3ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6325647 | 0.90 | MMP2 (0.39) | SIGMAR1MMP3ALDH1A1PSEN1PSEN2 | |
| SCHEMBL6326033 | 0.81 | MMP2 (0.43) | MMP3ALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL6324718 | 0.78 | ADAMTS4 (0.34) | ALDH1A1SMN1; SMN2HTR7 | |
| SCHEMBL6328935 | 0.73 | TSHR (0.50) | ALDH1A1SMN1; SMN2MMP9MMP13 | |
| SCHEMBL6324141 | 0.72 | HRH3 (0.48) | ALDH1A1SMN1; SMN2MMP9MMP13 | |
| SCHEMBL6407532 | 0.70 | ADAMTS4 (0.36) | ALDH1A1SMN1; SMN2PSEN1PSEN2APH1B | |
| SCHEMBL6769197 | 0.70 | ADAMTS4 (0.36) | ALDH1A1SMN1; SMN2PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747027-B1 | SELECTIVELY INHIBITS IN VITRO ACTIVITY OF HUMAN MATRIX METALLOPROTEASE-13 OVER IN VITRO ACTIVITY OF HUMAN MATRIX METALLOPROTEASE-1 | PHARMACIA CORPORATION | 2004-06-08 | — | — | US | disclosed |