Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767711 | 0.89 | ADRB2 (0.39) | ADRA2CADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL6763713 | 0.78 | PTGS1 (0.39) | ADRB2ADRB1MEN1ALOX15KMT2A | |
| SCHEMBL6772769 | 0.76 | GRIN2D (0.37) | ADRB2ADRB1MEN1ALOX15KMT2A | |
| SCHEMBL6766881 | 0.75 | CA2 (0.40) | MEN1ALOX15KMT2AKDM4EALDH1A1 | |
| SCHEMBL6766418 | 0.74 | BRAF (0.42) | ADRB2ADRB1MEN1ALOX15KMT2A | |
| SCHEMBL6766609 | 0.74 | ALDH1A1 (0.45) | ADRB2ADRB1MEN1ALOX15KMT2A | |
| SCHEMBL6766305 | 0.71 | GRIN2D (0.38) | ADRB2ADRB1MEN1ALOX15KMT2A | |
| SCHEMBL5379137 | 0.71 | DAO (0.46) | ADRB2ADRB1MEN1ALOX15KMT2A | |
| SCHEMBL5388796 | 0.70 | DAO (0.50) | ADRB2ADRB1MEN1ALOX15KMT2A | |
| SCHEMBL6773618 | 0.70 | GRIN2D (0.40) | ADRB2ADRB1MEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |