Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | FES | P07332 | 1/20 | 0.35 |
| ▸ | FER | P16591 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763713 | 0.81 | PTGS1 (0.39) | BRAFADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6767711 | 0.78 | ADRB2 (0.39) | BRAFADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6766881 | 0.77 | CA2 (0.40) | ALDH1A1BRAFMEN1ALOX15KMT2A | |
| SCHEMBL6766418 | 0.77 | BRAF (0.42) | ALDH1A1POLBBRAFADRB2ADRB1 | |
| SCHEMBL6768294 | 0.74 | ADRA2C (0.39) | ALDH1A1SMN1; SMN2POLBBRAFADRB2 | |
| SCHEMBL6766689 | 0.73 | GRIN2D (0.38) | BRAFADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL25599218 | 0.71 | NR3C1 (0.53) | ALDH1A1SMN1; SMN2HTTPOLBPDPK1 | |
| SCHEMBL6767054 | 0.71 | GRIN2D (0.36) | BRAFADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL763349 | 0.70 | GRIA1 (0.52) | CYP1A2KDM4ECA12PARP1CA9 | |
| SCHEMBL6773041 | 0.70 | KDM4E (0.49) | HTTPOLBBRAFADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |