Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FSHR | P23945 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768403 | 0.84 | HDAC1 (0.50) | HDAC1MAPTDHODHPTGIRPRSS12 | |
| SCHEMBL23118205 | 0.82 | PTGIR (0.49) | MAPTDHODHPTGIRPRSS12PTPN7 | |
| SCHEMBL6529991 | 0.82 | NPC1 (0.55) | CA1CA2MAPTMEN1POLB | |
| SCHEMBL12060917 | 0.80 | GPR3 (0.54) | MAPTDHODHPTGIRRAB9APTPN7 | |
| SCHEMBL6490182 | 0.79 | KIF11 (0.64) | TRPV1CA1CA2HDAC1KMT2A | |
| SCHEMBL6526964 | 0.78 | INSR (0.52) | HDAC1MAPTMEN1POLBGAA | |
| SCHEMBL6484020 | 0.76 | CA1 (0.45) | TRPV1CA1CA2MAPTMEN1 | |
| SCHEMBL6769890 | 0.76 | NPC1 (0.49) | HDAC1MAPTDHODHMEN1POLB | |
| SCHEMBL6690731 | 0.75 | CA1 (0.54) | TRPV1CA1CA2MEN1KMT2A | |
| SCHEMBL5184746 | 0.74 | CA1 (0.70) | TRPV1CA1CA2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800656-B2 | Tricyclic compounds and method of treating herpes virus | WARNER LAMBERT COMPANY | 2004-10-05 | — | — | US | claimed |