Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768403 | 0.84 | HDAC1 (0.50) | MAPTPTGIRDHODHGPR3HDAC1 | |
| SCHEMBL6526964 | 0.78 | INSR (0.52) | MAPTPTGIRHDAC1MEN1POLB | |
| SCHEMBL6497967 | 0.77 | NPC1 (0.48) | NPC1MAPTMEN1GAAKMT2A | |
| SCHEMBL6770347 | 0.76 | TRPV1 (0.54) | MAPTPTGIRDHODHHDAC1MEN1 | |
| SCHEMBL6529991 | 0.76 | NPC1 (0.55) | NPC1MAPTMEN1POLBGAA | |
| SCHEMBL6526369 | 0.74 | MAPT (0.55) | NPC1MAPTMEN1POLBGAA | |
| SCHEMBL6527944 | 0.73 | MAPT (0.43) | MAPTPTGIRDHODHGPR3CRHBP | |
| SCHEMBL6775812 | 0.73 | MAPT (0.43) | MAPTPTGIRDHODHGPR3MEN1 | |
| SCHEMBL6528974 | 0.73 | MAPT (0.55) | MAPTPTGIRDHODHGPR3CRHBP | |
| SCHEMBL6768996 | 0.73 | RAB9A (0.45) | NPC1MAPTPTGIRDHODHGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800656-B2 | Tricyclic compounds and method of treating herpes virus | WARNER LAMBERT COMPANY | 2004-10-05 | — | — | US | claimed |