Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.52 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.52 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.52 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405695 | 0.84 | TAAR1 (0.59) | HPGDPLA2G1BATG4BTAAR1KMT2A | |
| SCHEMBL6773829 | 0.82 | CNR1 (0.55) | HPGDPLA2G1BATG4BLMNATAAR1 | |
| SCHEMBL29579676 | 0.81 | PDPK1 (0.68) | HPGDLMNAPDPK1KMT2AMEN1 | |
| SCHEMBL658196 | 0.81 | PDPK1 (0.68) | HPGDLMNAPDPK1KMT2AMEN1 | |
| SCHEMBL31439249 | 0.80 | PLA2G1B (0.55) | HPGDPLA2G1BATG4BTAAR1KMT2A | |
| SCHEMBL5628156 | 0.78 | LMNA (0.57) | HPGDPLA2G1BATG4BLMNATAAR1 | |
| SCHEMBL5318479 | 0.77 | MAPT (0.57) | HPGDLMNAPDPK1KMT2AMEN1 | |
| SCHEMBL2298164 | 0.77 | MAPT (0.58) | LMNATAAR1KMT2AMEN1PLAAT3 | |
| SCHEMBL28650574 | 0.77 | TAAR1 (0.55) | HPGDPLA2G1BATG4BTAAR1KMT2A | |
| Hydrochloric Acid SCHEMBL28654800 | 0.75 | HTT (0.54) | HPGDPLA2G1BATG4BTAAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703405-B2 | RESPIRATORY SYSTEM AND SLEEP DISORDERS; HPOTENSIVE AGENTS; ANTIISCHEMIC, ANTISTROKE, ANTIEDEMA, ANTISTROKE, ANTICARCINOGENIC, AND ANTIDIABETIC AGENTS; ATHEROSCLEROSIS, GALLSTONE TREATMENT | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-03-09 | — | — | US | disclosed |
| US-20030171580-A1 | Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171580-A1 | Substituted 4-phenyltetrahydroisoquinolinium salts, process for their preparation, their use as a medicament, and medicament containing them | ABCB11, SLC10A1, REN | HPGD 640/4885PLA2G1B 1712/4885ATG4B 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.