SCHEMBL676902

SCHEMBL676902

C[Si](O[SiH3])c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
CA4 P22748 1/20 0.32
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL991780 0.78 CA4 (0.41) TSHRCA4LMNAALOX12ACHE
SCHEMBL675369 0.72 LTA4H (0.32) TSHR
SCHEMBL5486213 0.72 CA4 (0.31) CA4
SCHEMBL9327347 0.70 LTA4H (0.35) TSHR
SCHEMBL6465841 0.68 ALDH1A1 (0.32) TSHR
SCHEMBL8719 0.67 TSHR (0.39) TSHRCA4LMNAALOX12ACHE
SCHEMBL7631451 0.67 TSHR (0.39) TSHRCA4LMNAALOX12ACHE
SCHEMBL55165 0.67
SCHEMBL38901 0.66 ALDH1A1 (0.40) TSHRCA4LMNAALOX12ACHE
SCHEMBL22607984 0.65 TSHR (0.37) TSHRCA4LMNAALOX12ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023167976-A2 PROTECTIVE GARMENT HAVING WATER AND OIL RESISTANCE BURLINGTON INDUSTRIES LLC (US) 2023-09-07 WO disclosed
US-20230276880-A1 Protective Garment Having Water and Oil Resistance BURLINGTON INDUSTRIES LLC 2023-09-07 US disclosed
US-11518883-B2 Curable silicone compositions ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2022-12-06 US disclosed
US-20200270454-A1 CURABLE SILICONE COMPOSITIONS ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2020-08-27 US disclosed
EP-3562889-A1 CURABLE SILICONE COMPOSITIONS Elkem Silicones Shanghai Co., Ltd. (CN) 2019-11-06 EP disclosed
US-10308208-B2 Airbag made from a fabric substrate coated on an exterior side and on an opposite interior side INTERNATIONAL TEXTILE GROUP, INC. (US) 2019-06-04 US disclosed
EP-2361283-B1 METHOD FOR PRODUCING MOLDED SILICONE RUBBER PRODUCTS USING LIQUID SILICONE RUBBER BLUESTAR SILICONES USA CORP (US) 2018-08-29 EP disclosed
WO-2018121706-A1 CURABLE SILICONE COMPOSITIONS ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2018-07-05 WO disclosed
EP-2382271-B2 COATING COMPOSITIONS AND TEXTILE FABRICS COATED THEREWITH BLUESTAR SILICONES (FR) 2018-02-28 EP disclosed
US-9714345-B2 Silicone elastomer material suitable for use in particular for making dental impressions BLUESTAR SILICONES FRANCE SAS (FR) 2017-07-25 US disclosed
US-6369184-B1 UNSATURATED POLYSILOXANE, SILICONE OIL, PLATINUM CATALYST; ADHESION PROMOTER COMPRISING ALKOXYLATED ORGANOSILANE, EPOXIDIZED ORGANOSILICON COMPOUND, AND CHELATE COMPOUND; WEAR AND WRINKLE RESISTANCE; AIR BAGS RHODIA CHIMIE (FR) 2002-04-09 US disclosed
EP-0578743-B1 UREA-ALDEHYDE CONDENSATES AND MELAMINE DERIVATIVES COMPRISING FLUOROCHEMICAL OLIGOMERS MINNESOTA MINING & MFG (US) 1998-06-03 EP disclosed
US-5453540-A Oil and water repellent, stain resistance, softener MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-26 US disclosed
EP-0578651-B1 ISOCYANATE DERIVATIVES COMPRISING FLUOROCHEMICAL OLIGOMERS MINNESOTA MINING & MFG (US) 1995-09-13 EP disclosed
US-5292796-A Waterproofing and oil repelling coatings for textiles; softness, wear resistance, antisoilants MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-03-08 US disclosed
EP-0578651-A1 ISOCYANATE DERIVATIVES COMPRISING FLUOROCHEMICAL OLIGOMERS. MINNESOTA MINING & MFG (US) 1994-01-19 EP disclosed
EP-0578743-A1 UREA-ALDEHYDE CONDENSATES AND MELAMINE DERIVATIVES COMPRISING FLUOROCHEMICAL OLIGOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-01-19 EP disclosed
US-5276175-A Endcapped oligomeric acrylate esters modified with polyisocyanate compounds and partially blocked with an oxime MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-01-04 US disclosed
WO-1992017517-A1 UREA-ALDEHYDE CONDENSATES AND MELAMINE DERIVATIVES COMPRISING FLUOROCHEMICAL OLIGOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-15 WO disclosed
WO-1992017635-A1 ISOCYANATE DERIVATIVES COMPRISING FLUOROCHEMICAL OLIGOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-10-15 WO disclosed