Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767731 | 0.89 | FFAR4 (0.39) | S1PR4S1PR1S1PR3PPARAALDH1A1 | |
| SCHEMBL6769593 | 0.87 | L3MBTL1 (0.35) | S1PR1S1PR3TDP1 | |
| SCHEMBL13165876 | 0.85 | LTB4R (0.42) | TDP1NPC1RAB9AMAPT | |
| SCHEMBL5165561 | 0.82 | S1PR4 (0.41) | S1PR4S1PR1S1PR3PPARAALDH1A1 | |
| SCHEMBL6775391 | 0.81 | S1PR1 (0.38) | S1PR4S1PR1S1PR3PPARAALDH1A1 | |
| SCHEMBL3511485 | 0.79 | S1PR1 (0.36) | S1PR1S1PR3S1PR5NPC1 | |
| SCHEMBL3512684 | 0.79 | S1PR1 (0.36) | S1PR1S1PR3S1PR5NPC1 | |
| SCHEMBL5167524 | 0.79 | S1PR4 (0.43) | S1PR4S1PR1S1PR3PPARAALDH1A1 | |
| SCHEMBL13165878 | 0.78 | S1PR1 (0.34) | S1PR4S1PR1S1PR3S1PR5NPC1 | |
| SCHEMBL3511760 | 0.77 | NAMPT (0.40) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | claimed |