Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890392 | 0.89 | L3MBTL1 (0.35) | L3MBTL1KDM4EPOLBS1PR1S1PR3 | |
| SCHEMBL6769650 | 0.87 | S1PR4 (0.39) | S1PR1S1PR3TDP1 | |
| SCHEMBL13165876 | 0.87 | LTB4R (0.42) | FAAHLTB4RTDP1ACHE | |
| SCHEMBL6768150 | 0.83 | POLB (0.37) | L3MBTL1KDM4EPOLBS1PR1S1PR3 | |
| SCHEMBL6774202 | 0.82 | L3MBTL1 (0.39) | L3MBTL1KDM4EPOLBLTB4RTDP1 | |
| SCHEMBL3511485 | 0.79 | S1PR1 (0.36) | S1PR1S1PR3 | |
| SCHEMBL3512684 | 0.79 | S1PR1 (0.36) | S1PR1S1PR3 | |
| SCHEMBL13165878 | 0.78 | S1PR1 (0.34) | S1PR1S1PR3LTB4RACHE | |
| SCHEMBL3511760 | 0.77 | NAMPT (0.40) | KDM4E | |
| SCHEMBL3512678 | 0.77 | NAMPT (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | claimed |