SCHEMBL676972

SCHEMBL676972

CC[Sb](CC)C(C)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.43
LMNA P02545 1/20 0.43
AOC3 Q16853 2/20 0.39
TRPA1 O75762 5/20 0.38
HTR2A P28223 2/20 0.38
HRH1 P35367 1/20 0.38
RIPK1 Q13546 1/20 0.38
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
CYP2D6 P10635 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678015 0.79 POLB (0.39) TAAR1LMNAHTR2A
SCHEMBL677313 0.72 TAAR1 (0.42) TAAR1LMNAADRA2AADRA2CCYP2D6
Isopropylbenzene SCHEMBL27759170 0.69 TAAR1 (0.50) TAAR1LMNAAOC3TRPA1HTR2A
SCHEMBL677787 0.68 TAAR1 (0.39) TAAR1LMNAADRA2AADRA2CCYP2D6
SCHEMBL677100 0.68 SIGMAR1 (0.50) TAAR1TRPA1HTR2AADRA2CCYP2D6
Isopropylbenzene SCHEMBL11006422 0.68 TAAR1 (0.48) TAAR1LMNAADRA2AADRA2CCYP2D6
SCHEMBL17453236 0.67 TAAR1 (0.61) TAAR1LMNAAOC3TRPA1RIPK1
SCHEMBL136376 0.67 TAAR1 (0.61) TAAR1LMNAAOC3TRPA1RIPK1
SCHEMBL4443642 0.67 TAAR1 (0.61) TAAR1LMNAAOC3TRPA1RIPK1
Benzene SCHEMBL5290987 0.67 TAAR1 (0.61) TAAR1LMNAAOC3TRPA1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
EP-1767539-B1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-07-27 EP disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 TAAR1 184/4885LMNA 1912/4885AOC3 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.