SCHEMBL678015

SCHEMBL678015

CCCC[Sb](CCCC)C(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
TAAR1 Q96RJ0 4/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 1/20 0.38
HTR2A P28223 1/20 0.38
ASAH1 Q13510 1/20 0.36
ACER2 Q5QJU3 1/20 0.36
NAAA Q02083 2/20 0.36
SIGMAR1 Q99720 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL676972 0.79 TAAR1 (0.43) TAAR1LMNAHTR2A
SCHEMBL678385 0.73 SIGMAR1 (0.44) TAAR1SIGMAR1
Isopropylbenzene SCHEMBL8837125 0.72 HTR2A (0.47) POLBTAAR1ALDH1A1MAPTLMNA
Hexadecane SCHEMBL28192744 0.70 HTR2A (0.50) POLBTAAR1ALDH1A1LMNAHTR2A
Isopropylbenzene SCHEMBL18343980 0.70 HTR2A (0.50) POLBTAAR1ALDH1A1LMNAHTR2A
Isopropylbenzene SCHEMBL2596977 0.70 HTR2A (0.50) POLBTAAR1ALDH1A1LMNAHTR2A
SCHEMBL190051 0.68 RIPK1 (0.55) POLBTAAR1ALDH1A1SIGMAR1KDM4E
Fenipentol SCHEMBL21837 0.68 LMNA (0.64) POLBALDH1A1LMNAASAH1NAAA
Fenipentol SCHEMBL11351770 0.68 LMNA (0.64) POLBALDH1A1LMNAASAH1NAAA
Fenipentol SCHEMBL11573151 0.68 LMNA (0.64) POLBALDH1A1LMNAASAH1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
EP-1767539-B1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-07-27 EP disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 POLB 309/4885TAAR1 184/4885ALDH1A1 1542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.