Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 12/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779023 | 0.91 | GAA (0.40) | MAPK7HSD11B1EPHX2MGLLEGLN1 | |
| SCHEMBL6772904 | 0.91 | TLR7 (0.39) | HTR2BHSD11B1 | |
| SCHEMBL6773368 | 0.89 | TLR7 (0.43) | — | |
| SCHEMBL6768740 | 0.87 | NPC1 (0.42) | — | |
| SCHEMBL6773100 | 0.85 | RAB9A (0.46) | EPHX2 | |
| SCHEMBL6773545 | 0.81 | TLR7 (0.43) | — | |
| SCHEMBL6093363 | 0.81 | TLR7 (0.36) | — | |
| SCHEMBL6774530 | 0.80 | TRPV1 (0.42) | EPHX2 | |
| SCHEMBL6288804 | 0.79 | TLR7 (0.41) | — | |
| SCHEMBL6777973 | 0.79 | TLR7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |