Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 4/20 | 0.35 |
| ▸ | NPY1R | P25929 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772904 | 0.88 | TLR7 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL6773368 | 0.88 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6779023 | 0.87 | GAA (0.40) | TLR7EPHX2TLR8NUDT1 | |
| SCHEMBL6768740 | 0.86 | NPC1 (0.42) | RAB9ATLR7TLR8NUDT1 | |
| SCHEMBL6769722 | 0.85 | MAPK7 (0.42) | EPHX2 | |
| SCHEMBL6773840 | 0.84 | TLR7 (0.37) | TLR7TLR8NUDT1 | |
| SCHEMBL6768623 | 0.83 | CCR2 (0.43) | — | |
| SCHEMBL6773545 | 0.82 | TLR7 (0.43) | TLR7TLR8 | |
| SCHEMBL6774067 | 0.81 | ALDH1A1 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL6093363 | 0.81 | TLR7 (0.36) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |