Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | FASN | P49327 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773368 | 0.89 | TLR7 (0.43) | TLR7TLR8NAMPT | |
| SCHEMBL6773282 | 0.89 | P2RY12 (0.43) | TLR7TLR8CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6768623 | 0.88 | CCR2 (0.43) | — | |
| SCHEMBL6768740 | 0.87 | NPC1 (0.42) | TLR7TLR8 | |
| SCHEMBL6772904 | 0.84 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL6779023 | 0.83 | GAA (0.40) | TLR7TLR8 | |
| SCHEMBL6773100 | 0.82 | RAB9A (0.46) | TLR7TLR8 | |
| SCHEMBL6777740 | 0.82 | LMNA (0.46) | TLR7CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6769722 | 0.81 | MAPK7 (0.42) | — | |
| SCHEMBL6768596 | 0.80 | MCHR1 (0.47) | TLR7TLR8ADORA2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |