Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 2/20 | 0.42 |
| ▸ | CYBB | P04839 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5662541 | 0.80 | SCN9A (0.49) | ALDH1A1KDM4EHPGD | |
| SCHEMBL5663479 | 0.76 | HTR1B (0.58) | ALDH1A1KDM4EHPGDNCF1CYBB | |
| Trifluoroacetic Acid SCHEMBL6768943 | 0.75 | F10 (0.50) | KDM4EHPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL18301289 | 0.75 | KLKB1 (0.54) | NCF1KMT2AMEN1PLAUKLKB1 | |
| SCHEMBL6775414 | 0.75 | ROCK1 (0.41) | ALDH1A1KDM4EHPGDPLAUKLKB1 | |
| Hydrochloric Acid SCHEMBL5661310 | 0.75 | HTR1B (0.57) | ALDH1A1KDM4EHPGDNCF1CYBB | |
| SCHEMBL7425113 | 0.74 | MEN1 (0.51) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL6776349 | 0.73 | ROCK1 (0.46) | ALDH1A1NCF1MTNR1AMTNR1BPLAU | |
| Trifluoroacetic Acid SCHEMBL6769172 | 0.73 | L3MBTL1 (0.38) | ALDH1A1KDM4EHPGDNCF1CYBB | |
| SCHEMBL25394381 | 0.72 | MTNR1A (0.49) | ALDH1A1KDM4EHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |