Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 3/20 | 0.36 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769175 | 0.86 | RIPK1 (0.34) | NCF1CYBBRIPK1KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6770678 | 0.80 | F7 (0.33) | PLAU | |
| Trifluoroacetic Acid SCHEMBL30450237 | 0.73 | PTGDR2 (0.36) | NCF1KDM4EALDH1A1RAF1 | |
| SCHEMBL6770030 | 0.73 | ALDH1A1 (0.48) | NCF1CYBBKDM4EALDH1A1HTR1B | |
| SCHEMBL6775981 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1ATMPLAUPLAT | |
| SCHEMBL5662541 | 0.71 | SCN9A (0.49) | KDM4EALDH1A1HPGDATM | |
| SCHEMBL15990637 | 0.69 | KDM4E (0.41) | L3MBTL1KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6768943 | 0.69 | F10 (0.50) | KDM4EHPGD | |
| Trifluoroacetic Acid SCHEMBL23412963 | 0.68 | NCF1 (0.80) | NCF1CYBB | |
| SCHEMBL6770681 | 0.67 | KLKB1 (0.32) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825181-B1 | ORALLY ADMINISTRATED TO EXHIBIT A STRONG ANTICOAGULANT EFFECT BY INHIBITING ACTIVATED BLOOD- COAGULATION FACTOR X | AJINOMOTO CO., INC. (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1065200-A1 | AMINOISOQUINOLINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2001-01-03 | — | — | EP | disclosed |