Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 15/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.65 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pridinol SCHEMBL143298 | 0.80 | CHRM2 (1.00) | CYP2D6CHRM2HTR1ACHRM1OPRM1 | |
| SCHEMBL2930093 | 0.79 | ALDH1A1 (0.62) | CCR2CHRM2HTR1ACHRM1OPRM1 | |
| SCHEMBL7298771 | 0.78 | CCR2 (0.64) | CCR2CYP2D6CHRM2HTR1ACHRM1 | |
| Pridinol SCHEMBL27496509 | 0.78 | CHRM2 (0.97) | CYP2D6CHRM2HTR1ACHRM1OPRM1 | |
| Pridinol SCHEMBL29250415 | 0.78 | CHRM2 (0.97) | CYP2D6CHRM2HTR1ACHRM1OPRM1 | |
| Pridinol SCHEMBL363996 | 0.78 | CHRM2 (0.97) | CYP2D6CHRM2HTR1ACHRM1OPRM1 | |
| SCHEMBL5591791 | 0.77 | ALDH1A1 (0.58) | CCR2CYP2D6CHRM2HTR1ACHRM1 | |
| SCHEMBL10685802 | 0.75 | KDM4E (0.69) | CHRM2KCNH2SIGMAR1KDM4ECHRM4 | |
| SCHEMBL23851111 | 0.74 | ALDH1A1 (0.87) | CYP2D6SIGMAR1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL10502937 | 0.74 | KDM4E (0.67) | CHRM2KCNH2SIGMAR1KDM4ECHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-0914319-B1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LTD (JP) | 2001-11-21 | — | — | EP | disclosed |