Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.55 |
| ▸ | MMP13 | P45452 | 17/20 | 0.55 |
| ▸ | MMP3 | P08254 | 8/20 | 0.55 |
| ▸ | MMP9 | P14780 | 7/20 | 0.55 |
| ▸ | MMP2 | P08253 | 7/20 | 0.55 |
| ▸ | MMP7 | P09237 | 5/20 | 0.55 |
| ▸ | MMP14 | P50281 | 2/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 15/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.48 |
| ▸ | ADAM9 | Q13443 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770279 | 1.00 | MMP1 (0.55) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6769330 | 0.90 | MMP1 (0.63) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6769326 | 0.90 | MMP1 (0.63) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6768522 | 0.90 | MMP1 (0.60) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6768521 | 0.90 | MMP1 (0.60) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6768791 | 0.87 | MMP1 (0.55) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6768788 | 0.87 | MMP1 (0.55) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6768692 | 0.85 | MMP1 (0.62) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6769757 | 0.84 | MMP1 (0.52) | MMP1MMP13MMP3MMP9MMP2 | |
| SCHEMBL6769750 | 0.84 | MMP1 (0.52) | MMP1MMP13MMP3MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686355-B2 | TREATING HEART DISEASE, MULTIPLE SCLEROSIS, ARTHRITIS, ATHEROSCLEROSIS, AND OSTEOPOROSIS; ANTICANCER AGENTS | WARNER-LAMBERT COMPANY | 2004-02-03 | — | — | US | disclosed |
| US-20020156074-A1 | Biphenyl sulfonamides useful as matrix metalloproteinase inhibitors | BARVIAN NICOLE CHANTEL (US) | 2002-10-24 | — | — | US | disclosed |
| EP-1233016-A1 | Biphenyl sulfonamides useful as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2002-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156074-A1 | Biphenyl sulfonamides useful as matrix metalloproteinase inhibitors | MMP3, MMP9, MMP13 | MMP1 5/4885MMP13 3/4885MMP3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.