Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390537 | 0.82 | RECQL (0.51) | CA12CA1CA2CA9GRIN2D | |
| SCHEMBL2184685 | 0.77 | CYP2C9 (0.37) | CA12CA1CA2CA9GRIN2D | |
| SCHEMBL45768 | 0.77 | CA12 (0.57) | CA12CA1CA2CA9GRIN2D | |
| SCHEMBL1988774 | 0.75 | KMT2A (0.47) | GAAALDH1A1CYP2C9POLBMAPT | |
| SCHEMBL5841879 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL3065003 | 0.75 | CA12 (0.55) | CA12CA1CA2CA9GRIN2D | |
| Fluoride SCHEMBL27718975 | 0.75 | CA12 (0.55) | CA12CA1CA2CA9GRIN2D | |
| Iodide SCHEMBL28867266 | 0.75 | CA12 (0.55) | CA12CA1CA2CA9GRIN2D | |
| SCHEMBL3672272 | 0.74 | CYP2C9 (0.48) | CA12CA1CA2CA9GRIN2D | |
| Sulfuric Acid SCHEMBL4014385 | 0.73 | GAA (0.49) | CA12CA1CA2CA9GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723480-A | Adhesion receptor antagonists III | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-03 | — | — | US | claimed |
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | claimed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | claimed |
| US-10112893-B2 | Guanidinium compounds | NUTECH VENTURES (US) | 2018-10-30 | — | — | US | disclosed |
| US-20170001954-A1 | GUANIDINIUM COMPOUNDS | NUTECH VENTURES (US) | 2017-01-05 | — | — | US | disclosed |
| WO-2016201128-A1 | GUANIDINIUM COMPOUNDS | NUTECH VENTURES (US) | 2016-12-15 | — | — | WO | disclosed |
| US-6720344-B2 | BINDING TO NUCLEAR RECEPTOR PROTEINS; STIMULATING BMP-2 PROMOTER ACTIVITY | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2004-04-13 | — | — | US | disclosed |
| US-20030119791-A1 | Methods and compositions for stimulating osteoblast proliferation or treating malignant cell proliferation and methods for selecting osteoblast proliferation stimulants | KERWIN SEAN M (US) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119791-A1 | Methods and compositions for stimulating osteoblast proliferation or treating malignant cell proliferation and methods for selecting osteoblast proliferation stimulants | MKI67, HGF, AREG | CA12 2376/4885CA1 2296/4885CA2 1176/4885 |
| US-10112893-B2 | Guanidinium compounds | GDA, GMPS, GNAI3 | CA12 1977/4885CA1 2166/4885CA2 1261/4885 |
| US-20170001954-A1 | GUANIDINIUM COMPOUNDS | GDA, GMPS, GNAI3 | CA12 1977/4885CA1 2166/4885CA2 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.